Pathophysiology of itching in urticaria and atopic dermatitis
نویسندگان
چکیده
منابع مشابه
Atopic dermatitis model of itching behavior in hairless mice
In atopic dermatitis (AD), severe itching and scratching not only impacts the patient's quality of life, but also exacerbates the disease; however, the precise underlying mechanisms of itching in AD remain elusive. We have previously reported a special diet-induced, mouse model of AD. This article reviews the characteristics of the model, and the chronological and pharmacological analyses of th...
متن کاملItch in atopic dermatitis - pathophysiology and treatment.
Pruritus is an essential feature of atopic dermatitis with a high impact on the quality of life. Although the pathophysiology of atopic dermatitis itch is not fully understood, recent studies have demonstrated that a variety of mechanisms contribute to the induction and maintenance of the symptom. For example, an increased number of cutaneous nerve fibers and neuropeptides were identified in at...
متن کاملAtopic Dermatitis: From Pathophysiology to Diagnostic Approach
Atopic eczema/dermatitis syndrome (AEDS) is a chronic inflammatory skin disease, very common in childhood (1). The prevalence of AEDS is estimated to 15–30% in children and 2–10% in adults while the incidence has shown a 2to 3-fold increase in the past 3 decades in developed countries (2). This results in a significant socio-economic impact, that in the United States was estimated in a range fr...
متن کاملItch characteristics in five dermatoses: non-atopic eczema, atopic dermatitis, urticaria, psoriasis and scabies.
Itch is a frequent symptom in many diseases. Some studies have used questionnaires to evaluate pruritus by targeting a single type of dermatitis, for example, studying atopic dermatitis (AD) with the " Eppendorf Itch Questionnaire " (1, 2), and uraemic pruritus (3). Questionnaires have also been used to study psoriasis (4) and urticaria (5). The pathophysiological mechanisms of itch, especially...
متن کاملAssociation of LL-37 and IL-31 serum levels with SCORing Atopic Dermatitis (SCORAD) score in atopic dermatitis patients
Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic dermatitis. Myriad pieces of evidence have pointed to the major roles of LL-37 and interleukin-31 (IL31)in atopic dermatitis. The studies on atopic dermatitis are still limited i...
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ژورنال
عنوان ژورنال: Allergy
سال: 1992
ISSN: 0105-4538
DOI: 10.1111/j.1398-9995.1992.tb05091.x